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Saracino R
114(7):1176-1177
and is thus comparable to the effects of A-967079 on pinch-evoked activity in inflamed rats
2 μM) and MAPK3 (ERK1
9% of control by co-application of 5 μM 6
PF-05241328 Catalog No.:M20652-C Saracino RPF 05241328 is a potent and selective inhibitor of human Nav1. 7 voltage dependent sodium channels (Nav1. 7), with an IC50 of 31 nM. Product information CAS Number: 1387633 03 5 Molecular Weight: 436. 91 Formula: C19H21ClN4O4S Chemical Name: 1 [5 chloro 6 (2 methylpropoxy)pyridin 3 yl] N methanesulfonyl 3 methyl 1H indazole 5 carboxamide Smiles: CC1=NN(C2C=NC(OCC(C)C)=C(Cl)C=2)C2C=CC(=CC1=2)C(=O)NS(C)(=O)=O InChiKey: RVTSXVZXEGFIPW UHFFFAOYSA N InChi: